中文名稱：AP標(biāo)記的山羊抗人IgM

英文名稱：AP-conjugated Goat anti-human IgM

相關(guān)類別：AP標(biāo)記二抗

儲存：冷凍（-20℃）

標(biāo) 記物：AP

技術(shù)規(guī)格

Background

IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to its large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to its high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences.

Applications

1/2000-10000 for ELISA 1/1000-5000 for Western blotting 1/200-1000 for Immunohistochemistry/cytochemistry

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AP標(biāo)記的山羊抗人IgM