Name: PEG10抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： PEG10抗原（重組蛋白）

英文名稱： PEG10 Antigen (Recombinant Protein)

別名： EDR, HB-1, Mar2, MEF3L, Mart2, RGAG3

儲存： 冷凍（-20℃）

相關類別：抗原

概述

Fusion protein corresponding to C terminal 250 amino acids of human PEG10

技術規格

Full name:	paternally expressed 10
Synonyms:	EDR, HB-1, Mar2, MEF3L, Mart2, RGAG3
Swissprot:	Q86TG7
Gene Accession:	BC050659
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas.

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