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  • PTP4A2抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW17129
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:40
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文名稱: PTP4A2抗原(重組蛋白)

英文名稱: PTP4A2 Antigen (Recombinant Protein)

別       名: HH13; OV-1; PRL2; HH7-2; PRL-2; PTP4A; HU-PP-1; PTPCAAX2; ptp-IV1a; ptp-IV1b

儲       存: 冷凍(-20℃)

相關(guān)類別: 抗原

概述

Fusion protein corresponding to a region derived from 2-164 amino acids of human PTP4A2

技術(shù)規(guī)格

Full name:

protein tyrosine phosphatase type IVA, member 2

Synonyms:

HH13; OV-1; PRL2; HH7-2; PRL-2; PTP4A; HU-PP-1; PTPCAAX2; ptp-IV1a; ptp-IV1b

Swissprot:

Q12974

Gene Accession:

BC070182

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.

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