Name: SORBS2抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：SORBS2抗原（重組蛋白）

英文名稱： SORBS2 Antigen (Recombinant Protein)

別名： ARGBP2; PRO0618

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述：

Fusion protein corresponding to a region derived from 1-200 amino acids of human SORBS2

技術(shù)規(guī)格：

Full name:	sorbin and SH3 domain containing 2
Synonyms:	ARGBP2; PRO0618
Swissprot:	O94875
Gene Accession:	BC011883
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms.

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