中文名稱(chēng)： KRT222抗原（重組蛋白）

英文名稱(chēng)： KRT222 Antigen (Recombinant Protein)

別名： KA21; KRT222P

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類(lèi)別：抗原

概述

Full length fusion protein

技術(shù)規(guī)格

Full name:

keratin 222, type II

Synonyms:

KA21; KRT222P

Swissprot:

Q8N1A0

Gene Accession:

BC032815

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

KRT222, also known as KRT222P. KRT222 is a 295 amino acid protein belonging to the intermediate filament family. The gene encoding KRT222P has been listed as a pseudogene, however it has not been established that the protein is not translated, and is therefore treated as a protein coding gene. Existing as two alternatively spliced isoforms, the gene encoding KRT222P maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

展開(kāi)全部

KRT222抗原（重組蛋白）說(shuō)明書(shū)
下載

久久综合九九-久久综合九九亚洲一区-久久综合九色-久久综合九色欧美综合狠狠-久久综合九色婷婷97-久久综合九色综合8888

021-54845833/15800441009

ELISA試劑盒

PCR試劑盒

生化試劑盒

細(xì)胞系

細(xì)胞庫(kù)

基礎(chǔ)培養(yǎng)基

完全培養(yǎng)基

原代細(xì)胞

細(xì)胞專(zhuān)用培養(yǎng)基

菌株

生化試劑

病理染色液

科研抗體

標(biāo)準(zhǔn)品

血清

產(chǎn)品中心

最新產(chǎn)品

相關(guān)文章

KRT222抗原（重組蛋白）

Full name:	keratin 222, type II
Synonyms:	KA21; KRT222P
Swissprot:	Q8N1A0
Gene Accession:	BC032815
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	KRT222, also known as KRT222P. KRT222 is a 295 amino acid protein belonging to the intermediate filament family. The gene encoding KRT222P has been listed as a pseudogene, however it has not been established that the protein is not translated, and is therefore treated as a protein coding gene. Existing as two alternatively spliced isoforms, the gene encoding KRT222P maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.