購(gòu)物車
幫助
021-54845833/15800441009
相關(guān)類別： 抗原
概 述
Full length fusion protein
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Full name: |
proline rich 5 (renal) |
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Synonyms: |
PP610; PROTOR1; PROTOR-1; FLJ20185k |
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Swissprot: |
P85299 |
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Gene Accession: |
BC016921 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. |
