久久综合九九-久久综合九九亚洲一区-久久综合九色-久久综合九色欧美综合狠狠-久久综合九色婷婷97-久久综合九色综合8888

歡迎來到上海通蔚!

021-54845833/15800441009

品質(zhì)保證 · 通蔚試劑

當(dāng)前位置: 首頁 > 科研產(chǎn)品 > 科研抗體 > 一抗 > 兔抗FOXO1/3/4多克隆抗體

產(chǎn)品中心

  • 兔抗FOXO1/3/4多克隆抗體

    規(guī)格:
    數(shù)量:

    購買數(shù)量

    價格:
    • 品牌 : 通蔚生物
    • 目錄號 : TW21442
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:75
  • 商品詳情
  • 參考文獻
  • 說明書下載
  • 商品評論0
  • 相關(guān)產(chǎn)品

中文名稱:兔抗FOXO1/3/4多克隆抗體

英文名稱: Anti-FOXO1/3/4 rabbit polyclonal antibody

別      名: FKH1; FKHR; FOXO1A/FOXO2; AF6q21; FKHRL1; FOXO3A; FKHRL1P2/AFX; AFX1; MLLT7

儲      存: 冷凍(-20℃) 避光

抗      原: FOXO1/3/4

宿      主: Rabbit

反應(yīng)種屬: Human Mouse

相關(guān)類別: 一抗

標(biāo)  記 物: Unconjugate

克隆類型: Unconjugate

技術(shù)規(guī)格

Background:

Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts syngernistically with ATF4 to suppress osteocalcin/BGLAP activity, increasing glucose levels and triggering glucose intolerance and insulin insensitivity. Also suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP. In hepatocytes, promotes gluconeogenesis by acting together with PPARGC1A to activate the expression of genes such as IGFBP1, G6PC and PPCK1. Important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1. Promotes neural cell death. Mediates insulin action on adipose. Regulates the expression of adipogenic genes such as PPARG during preadipocyte differentiation and, adipocyte size and adipose tissue-specific gene expression in response to excessive calorie intake. Regulates the transcriptional activity of GADD45A and repair of nitric oxide-damaged DNA in beta-cells.

Applications:

IHC

Name of antibody:

FOXO1/3/4

Immunogen:

Synthesized peptide derived from Internal of human FOXO1/3/4-pan.

Full name:

forkhead box O1/3/4

Synonyms:

FKH1; FKHR; FOXO1A/FOXO2; AF6q21; FKHRL1; FOXO3A; FKHRL1P2/AFX; AFX1; MLLT7

SwissProt:

Q12778/O43524/P98177

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100


主站蜘蛛池模板: 2018天天操 | 久久国产精品夜色 | 国产一区二区亚洲精品天堂 | 欧美亚洲高清日韩成人 | 曰本lesxxxx在线观看视频 | www.狠狠| 六月丁香婷婷激情国产 | 亚洲另类精品综合 | 免费网站啪啪大全 | 亚洲欧美精品在线 | 欧美福利视频在线 | 一区二区三区欧美在线 | 一级有奶水毛片免费看 | 日韩欧免费一区二区三区 | 久久99精品久久久久久三级 | 十八女人毛片 | 深夜福利视频网址 | 日日噜噜噜夜夜爽爽狠狠图片 | 久久毛片免费看 | 在线观看麻豆国产精品 | 久久99国产精品久久欧美 | 日本伊人精品一区二区三区 | 国产亚洲欧美一区二区 | 又黄又爽又色的免费毛片 | 色综合天天综一个色天天综合网 | 国产成人精视频在线观看免费 | 91热国内精品永久免费观看 | 欧美亚洲综合另类成人 | 四虎影在永久在线观看 | 国产成人亚洲综合小说区 | 热玖玖| 在线一区播放 | 欧美激情精品久久久久久久 | 性感美女一级毛片 | 欧美a级成人淫片免费看 | 国产一区在线观看免费 | 免费观看视频成人国产 | 国产日本亚洲欧美 | 亚洲免费在线视频 | 成人免费网站久久久 | 日韩在线操 |