購(gòu)物車
幫助
021-54845833/15800441009
中文名稱： 兔抗PSMC5多克隆抗體
英文名稱： Anti-PSMC5 rabbit polyclonal antibody
別 名： S8; p45; SUG1; SUG-1; TBP10; TRIP1; p45/SUG; PSMC5
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃） 避光
宿 主： Rabbit
抗 原： PSMC5
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
WB |
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Name of antibody: |
PSMC5 |
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Immunogen: |
Fusion protein of human PSMC5 |
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Full name: |
proteasome (prosome, macropain) 26S subunit, ATPase, 5 |
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Synonyms： |
S8; p45; SUG1; SUG-1; TBP10; TRIP1; p45/SUG; PSMC5 |
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SwissProt: |
P62195 |
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WB Predicted band size: |
46 kDa |
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WB Positive control: |
A431 and HepG2 cells |
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WB Recommended dilution: |
500-2000 |
