中文名稱：兔抗GRM1多克隆抗體

英文名稱： Anti-GRM1 rabbit polyclonal antibody

別名： GRM1A, mGlu1, GPRC1A, MGLUR1, SCAR13, MGLUR1A

相關(guān)類別：一抗

儲(chǔ) 存： 冷凍（-20℃）

宿主： Rabbit

抗原： GRM1

反應(yīng)種屬： Human, Mouse, Rat

標(biāo) 記物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The canonical alpha isoform of the metabotropic glutamate receptor 1 gene is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. Alternative splicing results in multiple transcript variants encoding distinct isoforms; some of which may have distinct functions.

Applications:

ELISA, IHC

Name of antibody:

GRM1

Immunogen:

Synthetic peptide of human GRM1

Full name:

glutamate receptor, metabotropic 1

Synonyms：

GRM1A, mGlu1, GPRC1A, MGLUR1, SCAR13, MGLUR1A

SwissProt:

Q13255

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human colon cancer and Human ovarian cancer

IHC Recommend dilution:

10-50

展開全部

兔抗GRM1多克隆抗體說(shuō)明書
下載

久久综合九九-久久综合九九亚洲一区-久久综合九色-久久综合九色欧美综合狠狠-久久综合九色婷婷97-久久综合九色综合8888

021-54845833/15800441009

ELISA試劑盒

PCR試劑盒

生化試劑盒

細(xì)胞系

細(xì)胞庫(kù)

基礎(chǔ)培養(yǎng)基

完全培養(yǎng)基

原代細(xì)胞

細(xì)胞專用培養(yǎng)基

菌株

生化試劑

病理染色液

科研抗體

標(biāo)準(zhǔn)品

血清

產(chǎn)品中心

最新產(chǎn)品

相關(guān)文章

兔抗GRM1多克隆抗體

Background:	L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The canonical alpha isoform of the metabotropic glutamate receptor 1 gene is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. Alternative splicing results in multiple transcript variants encoding distinct isoforms; some of which may have distinct functions.
Applications:	ELISA, IHC
Name of antibody:	GRM1
Immunogen:	Synthetic peptide of human GRM1
Full name:	glutamate receptor, metabotropic 1
Synonyms：	GRM1A, mGlu1, GPRC1A, MGLUR1, SCAR13, MGLUR1A
SwissProt:	Q13255
ELISA Recommended dilution:	1000-2000
IHC positive control:	Human colon cancer and Human ovarian cancer
IHC Recommend dilution:	10-50