中文名稱: 兔抗ZBTB10多克隆抗體
技術(shù)規(guī)格
Background: |
RINZF, also known as ZBTB10 (zinc finger and BTB domain containing protein 10), is a 847 amino acid protein that contains one BTB/POZ domain and two C2H2-type zinc fingers. Localized to the nucleus, RINZF is believed to play a role in transcriptional regulation. Specifically, RINZF is capable of binding to the CACC element of the Gastrin promoter. In this regard, RINZF competes with Sp1 for CACC binding and interferes with Sp1 transactivation, thereby regulating Gastrin gene expression. The rat RINZF protein shares 98% homology with the human RINZF protein, suggesting that RINZF is a conserved protein. Due to alternative splicing events, two RINZF isoforms exist. In addition, RINZF may be phosphorylated by ATR or ATM upon DNA damage. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
ZBTB10 |
Immunogen: |
Synthetic peptide of human ZBTB10 |
Full name: |
zinc finger and BTB domain containing 10 |
Synonyms: |
RINZF |
SwissProt: |
Q96DT7 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human colorectal cancer and human tonsil |
IHC Recommend dilution: |
50-300 |
WB Predicted band size: |
95 kDa |
WB Positive control: |
Jurkat cell lysate |
WB Recommended dilution: |
500-2000 |