Name: 兔抗HLA-DOB多克隆抗體
Brand: 通蔚生物

中文名稱(chēng)：兔抗HLA-DOB多克隆抗體

英文名稱(chēng)： Anti-HLA-DOB rabbit polyclonal antibody

別名： major histocompatibility complex, class II, DO beta; DOB; HLA_DOB

相關(guān)類(lèi)別：一抗

儲(chǔ) 存： 冷凍（-20℃）

宿主： Rabbit

抗原： HLA-DOB

反應(yīng)種屬： Human

標(biāo) 記物： Unconjugate

克隆類(lèi)型： rabbit polyclonal

技術(shù)規(guī)格

Background:	HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.
Applications:	ELISA, IHC
Name of antibody:	HLA-DOB
Immunogen:	Synthetic peptide of human HLA-DOB
Full name:	major histocompatibility complex, class II, DO beta
Synonyms:	DOB; HLA_DOB
SwissProt:	P13765
ELISA Recommended dilution:	5000-10000
IHC positive control:	Human tonsil
IHC Recommend dilution:	40-200