中文名稱:AAK1抗原(重組蛋白)
英文名稱: AAK1 Antigen (Recombinant Protein)
儲 存: 冷凍(-20℃)
相關類別: 抗原
概述
Fusion protein corresponding to N terminal 236 amino acids of human AAK1 |
技術規格
Full name: |
AP2 associated kinase 1 |
Swissprot: |
Q2M2I8 |
Gene Accession: |
BC002695 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. |